The purpose of the study is to evaluate the physical performance of a Biograph mCT Flow R PET/CT system (Siemens Healthcare, Germany) and to. to fundamentally change how PET imaging is performed. Powered by Siemens’ revolutionary FlowMotion™ technology,. Biograph mCT Flow™ is the world’s first. Biograph mCT Flow with FlowMotion™ technology combines our standard- setting PET/CT with a unique system design that enables continuous motion of.
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No attenuation and scatter correction and no post-smoothing filter were applied. Ethical approval All procedures performed in studies involving human participants were approved by the regional mctt committee and were in accordance with the Helsinki declaration.
Biograph mCT 20 Excel
The advantage of the continuous bed motion is the increase of uniformity in the sensitivity profile across the axial FOV, due to the fact that the density of lines of response LOR does not depend of their axial bioggraph as in the case of SS acquisitions [ 13 ]. The expected value of the true count rate is gained by a fit through all mcr below the peak NECR standard as opposed to the extrapolated values from the last three acquisitions standard. The CRCs were similar in both acquisition modes. Of note, the standard permits for a range of image reconstruction methods.
Whole-body images were compared visually by two experienced imaging specialists one nuclear medicine physician and one imaging physicist.
Using this acquisition mode, the patient is moved through the gantry while PET emission data is continuously acquired. No noticeable differences were found between the two systems.
The elevated background variability is assumed to be caused by the choice of the table speed and the data processing techniques specific to CTM acquisitions.
Biograph mCT – Siemens Healthineers Global
This can be attributed in part to the generation of Gibbs biographh at the edge of the reconstructed object, which are particularly noticeable in smaller objects [ 2529 ]. This article has been cited by other articles in PMC. The first and the last slice of the acquisitions were excluded from this evaluation. The axial end slices first and last slice were excluded hiograph the analysis.
National Electrical Manufacturers Association. Received Jun 15; Accepted Oct Characterization of sampling schemes for whole body PET imaging. Previous studies have shown that by incorporating PSF modeling into the image reconstruction, an overestimation of the CRC can be observed, in particular, when no post-filtering is applied [ 252829 ].
The measurements were performed at the center biogtaph the FOV and at cm radial offset.
Biograph mCT Flow
This technique was proposed by Dahlbom and colleges in [ 13 ] and integrated in a first PET-only system in [ 14 ]. While the difference in error may be small, the exclusion of the end slices as permitted in the NEMA NU protocol should be followed anyway, as these end slices often suffer from high noise levels due to the low sensitivity of the scanner at the end of the axial FOV Fig.
This is further supported by the findings of Braun and colleges [ 34 ] who showed increased noise in CTM acquisitions in comparison to SS acquisitions with equivalent numbers of true events. Open in a separate window. Table speeds range from 0.
The four smallest spheres were filled with a target-to-background ratio TBR of 8: National Center for Biotechnology InformationU. Benefit of time-of-flight in PET: The CTM viograph followed the sequential subsequently. We thank Alexander Haug Vienna for helping with the clinical comparison of the images.
For the purpose of comparison between systems, this may not be sufficiently accurate. Furthermore, the accuracy of scatter and attenuation corrections in both acquisition modes was evaluated.
National Electical Manufacturers Association. For the measurements for the sensitivity, the count rate performance, and the associated relative count biograoh error, a provision was made in NEMA NU for elevating the phantoms, if the vertical range of the patient table is insufficient for the required placement of the phantoms.
Data were acquired at three transaxial locations xy: Data were reconstructed with an ordered-subset expectation maximization OSEM [ 25 ] 3D iterative algorithm, using 2 iterations i and 24 subsets sand additionally with 2 iterations and 21 subsets applying PSF correction and TOF.
The extra bed position information is then employed during the data processing, thus, assuring that the final reconstructed images contain the correct position information. The count rate error evaluation was also slightly modified in the standard. The average and range percent contrast obtained for hot and cold spheres, the average and range standard deviation of the background counts, and the mean residual error in scatter and attenuation corrections were evaluated.
The maximum and minimum errors for all activity concentrations are depicted in Fig.
Biograph mCT 20 Excel – Siemens Healthineers Global
Within the SS protocol, the table is in a fixed position during an acquisition of data in the FOV and subsequently moves to the next position to acquire data of an axial range greater than the axial FOV of the system. All authors read and approved the final manuscript. Accuracy of count losses and random corrections For this evaluation, the measurements acquired for the evaluation of the scatter fraction and count rate performance was used.
The sphere-to-background ratio is 4: However, this study was performed on a different system with an axial FOV of