Ameloblastic carcinoma is a rare form of odontogenic tumor, one that develops in the jawbones from the epithelial cells that generate the tooth enamel. Mandible / maxilla – Malignant tumors: ameloblastic carcinoma. Ameloblastic carcinoma is a rare odontogenic malignancy that combines the histological features of ameloblastoma with cytological atypia.

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Whereas ameloblastic carcinoma exhibit malignant features, such as cellular atypia and mitosis 3.

The tumor was negative for carcinoembryonic antigen. Ameloblastic carcinoma of the maxilla: One study has shown that malignant transformation requires a relatively long duration, and multistage carcinogenesis is a reasonable suggestion as to the underlying mechanism of malignant transformation The diagnosis of ameloblastic carcinoma is reserved for tumors that demonstrate a malignant morphologic appearance, regardless of whether metastasis is a proven fact at the time of discovery and treatment.

Ameloblastoma followed by metastatic ameloblastoma and finally ameloblastic carcinoma Ameloblastoma Histologically, may share some of same features such as peripheral carcinkma, reverse polarization and stellate reticulum, but should not show features of malignancy pleomorphism with hyperchromasia, atypical mitoses Clear cell odontogenic carcinoma Malignant epithelial odontogenic tumor composed primarily of nests and islands of clear cells May have focal peripheral palisading similar to ameloblastoma, but not as much cytologic atypia as ameloblastic ameloblaxtic More common in anterior mandible EWSR mutation Malignant ameloblastoma Like amelobastoma histologically but termed “malignant” after discovery ameloblastlc metastases Should not show any cytologic features of malignancy Metastatic disease Primary intraosseous squamous cell carcinoma Carcinoma composed of moderately to poorly differentiated squamous epithelial cells with variable keratinization Also derived from odontogenic epithelium.


Ameloblastic carcinoma of the maxillary sinus. N2 – The maxilla is an unusual site for an ameloblastoma, and certainly for an ameloblastic carcinoma.

Recently, a classification system was published differentiating between malignant odontogenic carcinoma variants. A reappraisal of the role of megavoltage irradiation. Furthermore, ameloblastic carcinoma exhibit histological features of ameloblastoma and carcinoma.

Lucca et al [ 9 ]. Naik V and Kale AD: Metastasizing ameloblastoma is defined as an ameloblastoma, which metastasizes and the primary and metastatic tissues demonstrate benign histological features 2.

Ameloblastic carcinoma – Wikipedia

By contrast, the majority of the patients treated at the West China Hospital of Stomatology were male and aged between 30 and 45 years. Click here for information on linking to our website or using our content or images.

How to cite this article: According to the World Health Organization WHOthe carcinoma can be classified as metastasizing malignant ameloblastoma or ameloblastic carcinoma 1. Few mitotic figures were also present.

Review and update of odontogenic carcinomas. Written informed consent was cwrcinoma from all patients and approval of the study was obtained from the Ethics Committee of Sichuan University.


Br J Oral Maxillofac Surg ; Additionally, potential tumor involvement of the surgical margins was observed. Tumors occurred more frequently in the mandible than in the maxillary Oncology Letters 8, no.

In addition, compared with the conventional radiotherapy, carbon ion carcinima exhibits less severe complications.

Ameloblastic carcinoma: An analysis of 12 cases with a review of the literature

In these patients, the male: The proposed mechanisms underlying the transformation of a classic benign ameloblastoma into a malignant tumor remain controversial.

It occurs more commonly in blacks than in whites [ 2 ]. Recently, Jensen et al 26 reported the ameloblastid of carbon ion therapy for recurrent ameloblastic carcinoma over four weeks, which showed no recurrence following three months. Br J Oral Maxillofac Surg ; A year review from Ibadan, Nigeria.

Rare Disease Database

Chemotherapy has not been indicated as a primary treatment Preoperative photograph of Case 2 showing swelling over left mid and lower face Click here to view. Secondary dedifferentiated carcinoma of the mandible: Fine-needle aspiration cytology of ameloblastic carcinoma of the maxilla: Keywords Ameloblastic carcinoma Ameloblastoma Malignant ameloblastoma. Maeloblastic information Article notes Copyright and License information Disclaimer.